The inheritance behavior of cancer as a simple Mendelian recessive TOGETHER WITH Some misconceptions regarding the relation of heredity to cancer and other diseases. Studies in the incidence and inheritability of spontaneous cancer in mice: 23rd report

By: Slye, Maud

Price: $75.00

Quantity: 1 available


1926 TWO OFFPRINTS (1 INSCRIBED BY AUTHOR) BY PIONEERING CANCER BIOLOGIST WHO DEMONSTRATED GENETIC HERITABILITY OF CANCER IN MOUSE MODELS. Two offprints 10 1/2 inches tall, printed blue paper covers (age-toned), stapled, 1 inscribed on cover, Compliments of the author, both very good. 1) The inheritance of cancer as a simple Mendelilan recessive, J Cancer Research, Vol X, April 1925, pages 15-49, unopened, 14 charts (pedigrees); 2) Some misconceptions regarding the relation of heredity to cancer and other diseases, JAMA, May 22, 1926, Vol. 86, 22 pages, 3 figures. MAUD SLYE (1879 - 1954) was an American pathologist who 'invented' genetically uniform mice as a research tool. Her work focused on the heritability of cancer in mice. She was also an advocate for the comprehensive archiving of human medical records, believing that proper mate selection would help eradicate cancer. She was nominated for the Nobel prize as a result of her work as one of the first scientists to suggest that cancer can be an inherited disease, and for the development of new procedures for the care and breeding of lab mice. Slye raised and kept pedigrees for 150,000 mice during her career. Reluctant to leave her mice to the care of her assistants, she once went twenty-six years without a vacation. GARRISON-MORTON No. 2652 Cancer and heredity. Ann. intern. Med. 1, 951-76, 1928. By selective breeding over a period of 15 years, Slye produced generations of mice absolutely resistant to, or particularly susceptible to, cancer. She demonstrated that resistance is a Mendelian dominant and susceptibility a recessive, either of which can be bred into or out of susceptible or resistant generations, according to the laws of genetics.

Title: The inheritance behavior of cancer as a simple Mendelian recessive TOGETHER WITH Some misconceptions regarding the relation of heredity to cancer and other diseases. Studies in the incidence and inheritability of spontaneous cancer in mice: 23rd report

Author Name: Slye, Maud

Categories: Medicine, Genetics, Cancer,

Edition: First editions

Publisher: Chicago, Journal of Cancer Research; American Medical Association: 1926

Inscription: Inscribed by author

Seller ID: 1005

Keywords: medicine; cancer; genetics; women